Mar 12, 2004 10:08
20 yrs ago
2 viewers *
English term
severity strata at baseline vs. severity at basline
English
Medical
Medical (general)
clinical trials
I've come across the expression "severity strata at baseline" because of a question asked by one of my Swedish colleagues and now I'd like to know if there is any meaningful difference between the two expressions above, or if the first expression is a bit tautological (it seems quite rare as well).
Cheers, Lisa
Cheers, Lisa
Responses
| 2 +1 | there appears to be a slight difference |
Jonathan MacKerron
|
| 4 +1 | see comment |
Craft.Content
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Responses
+1
15 mins
Jonathan MacKerron
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there appears to be a slight difference
based on Internet references, i.e. severity strata=a predefined range of severity versus "overall severity".
If they refer directly to these strata elsewhere than I'd say that it is important to differentiate, but without seeing the whole document who can say.
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Note added at 24 mins (2004-03-12 10:33:18 GMT)
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the strata might look like this, lower strata=mild/moderate; higher strata=severe/serious, but again just a guess on my part
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Note added at 29 mins (2004-03-12 10:38:36 GMT)
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the evaluators of such studies often use \"creative\" wording to put a postive spin on their findings, this may be such a case here
If they refer directly to these strata elsewhere than I'd say that it is important to differentiate, but without seeing the whole document who can say.
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Note added at 24 mins (2004-03-12 10:33:18 GMT)
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the strata might look like this, lower strata=mild/moderate; higher strata=severe/serious, but again just a guess on my part
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Note added at 29 mins (2004-03-12 10:38:36 GMT)
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the evaluators of such studies often use \"creative\" wording to put a postive spin on their findings, this may be such a case here
Peer comment(s):
| agree |
Vicky Papaprodromou
3 hrs
|
| neutral |
German Hernandez
: Big difference. When it mentiones a baseline strata it refers to a specific group. If it were just severity at baseline it would mean only for the base and would be no specific.
4 hrs
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4 KudoZ points awarded for this answer.
Comment: "Thanks Jonathan!"
+1
4 hrs
Craft.Content
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see comment
Presuming that there are 'n' parameters on which the groups were being tested, perhaps the strata refers to this statistic against which both the placebo and the treatment group were compared.
Hth.
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Note added at 4 hrs 59 mins (2004-03-12 15:08:01 GMT)
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Another synonym for \'strata\' might be \'spectrum\'/\'band\'.
Hth.
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Note added at 4 hrs 59 mins (2004-03-12 15:08:01 GMT)
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Another synonym for \'strata\' might be \'spectrum\'/\'band\'.
Discussion
after treatment, using standardized assessments for OCD, tics, anxiety ...
www.nimh.nih.gov/events/prstrepocd.cfm - 10k
"Significant improvements were observed for the treatment group compared with the placebo group independent of baseline severity strata."